{"id":"c26c1003-9323-474f-860c-434ddb931f54","title":"现代藏族人群全基因组变异数据","title_en":"Genomic variation data of modern Tibetans","serial":"","user_limit":"为尊重知识产权、保障数据作者的权益、扩展数据中心的服务、评估数据的应用潜力，请数据使用者在使用数据所产生的研究成果中（包括公开发表的论文、论著、数据产品和未公开发表的研究报告、数据产品等成果），明确注明数据来源和数据作者。对于转载（二次或多次发布）的数据，作者还须注明原始数据来源。","instructions":"以文本格式储存，文件名称为xxxx.vcf，xxxx表示样本在本实验室的编号。\n数据读取方式：可以直接用文本程序（如Editplus）打开。","description":"青藏高原平均海拔4000米以上，高寒、低氧等恶劣环境对人类的生存构成了巨大的挑战。然而，高原藏族人群自旧石器晚期就已经达到青藏高原，并且在新石器时期进一步大规模永久定居高海拔地区。因此，青藏高原的人群迁徙历史成为了近年来不同领域关注的焦点。为从全基因组的角度解析藏族人群的遗传结构，追溯人类定居高原的历史，我们获得了20个藏族个体的全基因组变异数据开展研究。采用DNA 微阵列（DNA Array）的方法，对20个样本进行了SNP分型检测，获得每个样品约70万位点（包括核基因组、线粒体DNA和Y染色体）分型结果。基于上述数据，进行相关生物信息分析（主要包括芯片位点质控分析、Y染色体和线粒体DNA的单倍群分型分析）。该数据有助于从核基因组、Y染色体和线粒体DNA的角度，解析藏族人群的遗传结构，通过与高原周边人群数据的比较，可以较为全面地追溯高原人群的迁徙和定居历史。","doi":"10.11888/Ecolo.tpdc.270370","projection":"","language":"zh","share_type":"protected","east":97.65,"west":85.52,"south":28.05,"north":32.28,"scale":null,"crs":null,"filesize":809.0,"share_policy":"c","ts_created":"2020-04-28T00:39:58.949277+08:00","doi_type":"拥有自主知识产权","ts_updated":"2021-04-19T21:32:42.319811+08:00","time_description":"","datas_group":0,"time_description_en":"","data_format":null,"project":[11],"specials":["f2a78cde-1c98-4241-94dc-7532eba32b80"],"cite":null,"review_status":5,"review_invite":[{"user_name":"于黎 ","username":"于黎","email":"yuli@ynu.edu.cn","is_cancel_expert":false}],"review_editor":{"id":42421,"last_login":"2022-04-08T15:16:51.670544+08:00","username":"任慧霞","email":"510727846@qq.com","is_active":true,"is_staff":true,"user_name":"任慧霞"},"data_sources":null,"temporal_resolution":"Yearly","spatial_resolution":"<= 1 m","license":"Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","fund":[6],"subtopics":{"metadata":"c26c1003-9323-474f-860c-434ddb931f54","three_pole":null,"third_pole":"XDA20040102"},"username":"XDA20040102","review_time":"2020-04-28T11:52:47.634740+08:00","protected_duration":24,"protected_describe":null,"is_important":false,"hit_count":1681}