{"id":"aaea3d74-ecd1-4c93-8de4-fa7aeaffcc85","title":"青藏高原藏族人群线粒体基因组测序数据集（V1.0)（2018）","title_en":"Mitochondrial DNA genome sequencing dataset of Tibetans for the Tibetan Plateau (Version 1.0) (2018)","serial":"","user_limit":"为尊重知识产权、保障数据作者的权益、扩展数据中心的服务、评估数据的应用潜力，请数据使用者在使用数据所产生的研究成果中（包括公开发表的论文、论著、数据产品和未公开发表的研究报告、数据产品等成果），明确注明数据来源和数据作者。对于转载（二次或多次发布）的数据，作者还须注明原始数据来源。","instructions":"fas格式，可以采用文字编辑器（如Editplus）和MEGA等打开查看和分析.","description":"采用高通量二代测序的方法，对671个藏族样本进行线粒体全基因组测序。测序平均深度1000×，确保每个样本的线粒体基因组完全覆盖（覆盖度100%）。基于系统发育思想，我们对这些数据进行质量控制，确保没有样本污染等质量问题。结合已发表的欧亚大陆其他人群的测序数据，系统研究藏族人群的母系遗传结构及其形成机制。结果表明，藏族人群中有20.98%可追溯至5.2-4.0 ka，与粟黍农业扩散至青藏高原的时间吻合。进一步分析表明，这些组分很可能于10-7 ka前起源于中国北方，与粟黍农业的起源和强化一致。因此，这些组分很可能代表了伴随粟黍农业传播进入青藏高原的粟黍农业人群。通过估算，这些组分在5.2-4.0 ka占藏族人群的40-50%。说明粟黍农业人群得迁徙极大地促进了对藏族人群的遗传结构形成。","doi":"10.11888/Paleoenv.tpdc.270255","projection":"","language":"zh","share_type":"online","east":97.17,"west":80.11,"south":28.35,"north":32.5,"scale":null,"crs":null,"filesize":10.6,"share_policy":"a","ts_created":"2018-12-29T11:39:53.918542+08:00","doi_type":null,"ts_updated":"2021-04-19T03:16:07.871498+08:00","time_description":"","datas_group":3,"time_description_en":null,"data_format":null,"project":[11],"specials":["f2a78cde-1c98-4241-94dc-7532eba32b80"],"cite":null,"review_status":5,"review_invite":[{"user_name":"张扬建","username":"naqu3228","email":"zhangyj@igsnrr.ac.cn","is_cancel_expert":true}],"review_editor":{"id":21054,"last_login":"2022-04-10T10:49:12.540341+08:00","username":"tingting","email":"panxd@itpcas.ac.cn","is_active":true,"is_staff":true,"user_name":"潘小多"},"data_sources":"","temporal_resolution":"","spatial_resolution":"","license":"Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","fund":[6],"subtopics":{"metadata":"aaea3d74-ecd1-4c93-8de4-fa7aeaffcc85","three_pole":null,"third_pole":"XDA20040102"},"username":"XDA20040102","review_time":null,"protected_duration":6,"protected_describe":null,"is_important":false,"hit_count":1684}