{"id":"9a4eeb11-7319-4550-b885-066c982dd0b9","title":"拉萨藏族人群线粒体基因组测序数据","title_en":"Mitochondrial genome sequencing data of Tibetan population in Lhasa","serial":"","user_limit":"为尊重知识产权、保障数据作者的权益、扩展数据中心的服务、评估数据的应用潜力，请数据使用者在使用数据所产生的研究成果中（包括公开发表的论文、论著、数据产品和未公开发表的研究报告、数据产品等成果），明确注明数据来源和数据作者。对于转载（二次或多次发布）的数据，作者还须注明原始数据来源。","instructions":"fas格式，可以采用文字编辑器（如Editplus）和MEGA等打开查看和分析","description":"采用高通量二代测序的方法，对68个藏族样本进行线粒体全基因组测序。测序平均深度1000×，确保每个样本的线粒体基因组完全覆盖（覆盖度100%）。基于系统发育思想，我们对这些数据进行质量控制，确保没有样本污染等质量问题。同时根据系统发育树，对每个个体进行单倍型类群划分。结果表明，拉萨藏族人群中M9a1a1c1b1a最高（19.12%），其次是G2（13.23%）、M13a（11.76%）、C4a（7.35%）、D4（7.35%）、A11a1a（5.88%）、M9a1b（5.88%），以及F1c、F1g、B4、F1d、M62b、F1a、F1b、G1、M10、M11、M8a、U7a、Z3a。从类群来源来看，包括了旧石器时期类群M13a、M62b、M9a1b等，来源于中国北方粟黍农业人群的M9a1a1c1b1a和A11a1a等，广泛分布于东亚南方的F1a等，分布于东亚北方的C4a、D4等类群。值得注意的是，拉萨藏族母系组分以中国北方粟黍农业人群组分为主，说明中国北方粟黍农业人群遗传输入对该地区人群遗传结构有着重要的影响。另外，从总体来看，拉萨藏族人群的母系遗传结构出现时间分层，可能代表了不同时期进入该地区的人群的遗传印记。","doi":"doi.org/10.1093/nsr/nwz080","projection":"","language":"zh","share_type":"protected","east":90.22,"west":92.09,"south":29.25,"north":30.18,"scale":null,"crs":null,"filesize":1.08,"share_policy":"c","ts_created":"2021-01-12T11:19:46.866664+08:00","doi_type":"沿用数据已有DOI","ts_updated":"2021-04-19T15:17:47.292223+08:00","time_description":"","datas_group":0,"time_description_en":"","data_format":null,"project":[11],"specials":["b6500306-f60b-4aa1-b0b6-0324d94866df","b6500306-f60b-4aa1-b0b6-0324d94866df"],"cite":null,"review_status":5,"review_invite":[{"user_name":"于黎 ","username":"于黎","email":"yuli@ynu.edu.cn","is_cancel_expert":false}],"review_editor":{"id":42421,"last_login":"2022-04-08T15:16:51.670544+08:00","username":"任慧霞","email":"510727846@qq.com","is_active":true,"is_staff":true,"user_name":"任慧霞"},"data_sources":null,"temporal_resolution":"Yearly","spatial_resolution":"1km - 10km","license":"Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","fund":[21],"subtopics":{"metadata":"9a4eeb11-7319-4550-b885-066c982dd0b9","three_pole":null,"third_pole":null},"username":"王利","review_time":null,"protected_duration":12,"protected_describe":null,"is_important":false,"hit_count":1212}